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Treatment B consisted of 385 mg BSE which contained 115 mol (50 mg) GR and 100 mg vitamin C (as ascorbic acid), and was reliant on gut bacteria to perform the conversion, which typically results in higher SF in colon and systemic locations, but overall lower total conversion 63,64
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Tirzepatide holds FDA approvals as Mounjaro for type 2 diabetes (2022) and as Zepbound for chronic weight management (2023) and for moderate-to-severe obstructive sleep apnea (2024), and it is EMA-approved as well
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doi:10.3390/mps7010017 Stone C, Harris DD, Broadwin M, et al
