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Description

However, there are conditions and risk factors that can compromise the endogenous production of glutathione by our liver and which are independent of our age

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Once released, the GR amino acids that interact with the drug are Phe209, Ala319, Ile350 and Val354 at a distance of 2 to 4 and also with residues Tyr180, Leu321, Lys318, Leu320, and Thr352 (Thr352 forms several polar and hydrogen bonding interaction at 2.2 to 3.2 ) that stabilizes the carmustine in the binding pocket (Fig

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