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In human HT-1080 fibrosarcoma cells, treatment of erastin (Era) restricts the production of glutathione ( Supplementary Figure S13 ), and therefore inactivates GPX4 and triggers ferroptosis (Yang et al., 2014)
2020 Mar;38(3):690.e1-690.e2
In a HF model with coarctation of the aorta, mice fed a high-cholesterol diet had higher TMAO levels and accelerated adverse ventricular remodeling (105)
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