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CagriSema's strategy of combining two proven mechanisms (amylin and GLP-1) in a single injection has produced strong Phase 3 results (20.4% weight loss), builds on the established semaglutide safety record, and is closest to market with an NDA filed

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Evidence suggests that discontinuation of treatment may be associated with a gradual return of appetite and potential weight regain if no ongoing support is in place

A novel human-based receptor antagonist of sustained action reveals body weight control by endogenous GLP-1