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Reprod Fertil Dev 2019;31(1):105-117

doi: 10.3389/fphar.2018.00388 Received 26 January 2018 Accepted 04 April 2018 Published 18 April 2018 Volume 9 - 2018 Edited by Olavi R

Psychiatr Danub

DISCUSSION Increased production of PGE 2 is a key event associated with the pathogenesis of OA, and inhibitors of PGE 2 biosynthesis are increasingly used for the treatment of this disease and other conditions associated with elevated levels of PGE 2