Systematic Review Orthopaedic Sports Medicine (2025) The 2025 systematic review by Vasireddi, Hahamyan et al
As with any other type of peptide, the common side effects of retatrutide will include nausea, gastrointestinal discomfort, and overall fatigue
Some people notice nothing at all at this dose, and that is completely normal
Proven Strategies to Reduce Nausea and Manage Side Effects Eating small, nutrient-dense meals several hours before or after your weekly injection significantly reduces nausea severity and onset time
However, it may not be suitable for those with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2
This suggests the need for a follow-up program for early detection of hepatobiliary disease