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Together, these findings highlight that while ACE-inhibitory peptides remain the most extensively studied, peptide-based strategies in cardiovascular diseases potentially extend beyond blood pressure regulation to include vascular repair, plaque stabilization, and endothelial modulation
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Therefore, a detailed understanding of the regulation of apoptosis, growth inhibition, and DNA repair, besides the identification of defects in the death pathway, may provide insights into the mechanisms of clinically relevant drug resistance