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2023 Dec;193(12):1969-1987

are "compounded" rather than FDA-approved mass-market drugs

Research published in Scientific Reports demonstrates that aged mice treated with NNMT inhibitors showed approximately 40% greater grip strength compared to untreated controls, remarkably surpassing even the benefits achieved through intensive exercise alone, which produced only 20% improvement

Conventional therapies like physical therapy, occupational therapy, and intravenous immunoglobulin remain important

By increasing the expression of Vascular Endothelial Growth Factor (VEGF), it creates a richer blood supply in areas that are traditionally dead zones for circulation, like the ACL or the Achilles tendon [2, 7]