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Third, they support the safety of repeated treatment cycles, as prior exposure does not appear to sensitize the immune system
Common injection sites include the abdomen, thigh, and upper arm
This position is supported by the NICE Guideline and at the end of 2025 we launched our freely accessible Pernicious Anaemia and B12 Deficiency education programme to the NHS community
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Signs include: Hives or widespread rash beyond the injection site Swelling of face, lips, tongue, or throat Difficulty breathing or wheezing Rapid heartbeat Feeling faint or losing consciousness These symptoms require immediate medical attention
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