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The most interesting paper I read showed a big difference between real world results of using GLP-1s versus the results achieved in clinical trials

For weight-loss positioning, brands should explain this clearly to avoid consumer confusion

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While it does not directly cause nutrient loss, it often leads people to reduce fiber intake further, which compounds the problem of inadequate nutrition

Bocchio-Chiavetto, L

These results support the continued safe use of GLP-1 RAs in T2DM and obesity, although longer trials with cancer-specific endpoints are warranted