Zepbound is the first GLP-1/GIP (gastric inhibitory polypeptide) medication, which is thought to be more potent than GLP-1 alone
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By mimicking the GLP-1 hormone, the medication not only induces weight loss but also enhances insulin sensitivity and lowers blood glucose levels, effectively treating the underlying drivers of metabolic syndrome
Commoner B, Townsend J, Pake GE
Research suggests tirzepatide preserves lean muscle mass more effectively than GLP-1-only compounds, though this remains an active area of investigation