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doi:10.1016/S2213-8587(17)30085-2 Newsome, P

Cytokine-stimulated immune cells can also promote HPA axis activation and GC signaling by upregulating the production of corticotrophin-releasing hormone (CRH) in the hypothalamus (181)

Nevertheless, I maintain vigilant monitoring of the thyroid in patients on these medications, particularly for those using them longer than 612 months

In between-drug comparisons, tirzepatide 15 mg and 10 mg outperformed semaglutide 1.0 mg and 0.5 mg and tirzepatide 5 mg was superior to semaglutide 0.5 mg, while no differences were found between semaglutide 2.0 mg and any of the tirzepatide doses (ESM Table 9)

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