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This review highlights compounds such as baicalein [22], GA [20], CGA [23], sesamol [24, 36], Nano-Honokiol [27], Q3G [33], BME [40], ginger [38], Triphala [41], and pterostilbene [37] which consistently reduced levels of IL-1 and TNF- in the brain, with similar decreases observed for IL-6 across multiple interventions [20, 22, 23, 27, 33, 37, 40] and IL-2 specifically with BME [40]

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After an 1 h of magnetic stirring at room temperature, P3 (300 mg) was introduced into the reaction system