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In laboratory and animal studies, researchers have examined how it interacts with pathways involved in blood vessel formation and tissue repair
2021;11(11):e056601
Annu Rev Pharmacol Toxicol 43:23360 Dinkova-Kostova AT, Holtzclaw WD, Cole RN, Itoh K, Wakabayashi N, Katoh Y, Yamamoto M, Talalay P (2002) Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
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In nonenzymatic autoxidations, free ferrous iron interacts with hydrogen peroxide to form ferric iron and hydroxyl radicals, which commences the process of lipid peroxidation by detaching hydrogen from the bis-allylic position of PUFAs (Reis and Spickett, 2012)
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