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Although the combination of atezolizumab and PEGPH20 failed to achieve the primary endpoint of improved objective response rate (ORR) compared to chemotherapy regimens in both studies, the signal-seeking trial design accelerated proof-of-concept evaluation while minimizing patient exposure to suboptimal therapies
Encoding, consolidation, and retrieval of contextual memory: differential involvement of dorsal CA3 and CA1 hippocampal subregions
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The exact causes of autoimmune disorders are not fully understood, but they are believed to result from a combination of genetic, environmental and lifestyle factors
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