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Oxidative stress occurs when there is an imbalance between free radicals (unstable molecules) and antioxidants in your body

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Key unanswered research questions What is the optimal dosing regimen: how often to administer, how long does effect last, when to retreat

Aside from genetic mutations, low intakes of vitamin B12, B6, and folate increase risk for hyperhomocysteinemia because they are required for the metabolism of methionine to cysteine