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Other clear candidates include patients with BMI 35+ who have tried and failed multiple structured weight loss approaches, patients with obesity plus severe sleep apnea, and patients with a metabolic syndrome phenotype where reducing insulin resistance matters

Our comprehensive analysis of stromal compartments underscores mitochondrial metabolic dysfunction in ABMR, emphasizing that the mechanisms underlying oxidative phosphorylation downregulation are highly cell type specific

Liraglutide (Saxenda) is another GLP-1 requiring daily rather than weekly injections but may suit certain patients

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But women with PCOS who meet the BMI eligibility criteria (BMI 27+ with a metabolic comorbidity, or BMI 30+) can access both through private prescription