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Sousa, L., Oliveira, M
In summary, a comprehensive analysis of 19 kinase candidates, which integrated LC-MS/MS data from several co-immunoprecipitations, in silico modeling, RNAi screening, and consensus sequence validation, identified KIN-19 as the most promising kinase candidate for further investigation
Its impaired integrity underlies the bioenergetic collapse that compromises immune function, while its release perpetuates the chronic inflammation characteristic of progressive HIV disease