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O'Brien et al., 2012)
However, studies conducted in non-deficient leptin adults have found relatively few effects on body weight limiting the utility of this hormone as an anti-obesity drug in those patients who do not have leptin insufficiency
(source) A 2017 meta-analysis did not support the suggestion that treatment with GLP-1 agonists or DPP-4 inhibitors increased all-cause mortality in type 2 diabetics
21.Davies MJ, Aroda VR, Rosenstock J, et al
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