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[1] [3] Other significant warnings include risks of pancreatitis, gallbladder disease, acute kidney injury with dehydration, diabetic retinopathy complications, and hypoglycemia when combined with insulin or sulfonylureas

This peptide has specific amino acid substitutions and a lipid modification that enhance its stability and prolong its interaction with the GLP-1 receptor, making it more suitable for extended studies than native GLP-1, which is rapidly broken down in the body

doi:10.1111/j.1463-1326.2012.01663.x