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Notably, women also appear to discontinue GLP-1 therapy more frequently because of gastrointestinal adverse effects than men in some cohorts (Brchers et al., 2024)

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A multicenter, randomized, double-blind, placebo-controlled trial demonstrated that liraglutide was associated with the resolution of non-alcoholic steatohepatitis (NASH) without worsening fibrosis

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572 To deepen our understanding of PRRs role in NDDs, we recommend reading recent reviews such as Innate Immune Activation in Neurodegenerative Diseases, 566 Targeting the NLRP3 Inflammasome for Neurodegenerative Disorders 573 and The Role of Toll-like Receptors and Neuroinflammation in Parkinsons Disease

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