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SKU: 8002685534
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Description

Is the acetate salt of a synthetic cyclic heptapeptide with the sequence cyclo-(Ac-Nle4-cyclo[Asp5-His6-D-Phe7-Arg8-Trp9-Lys10])-NH2, representing a conformationally constrained, metabolically stabilised derivative of the -MSH(4-10) pharmacophore core in which the Asp5 and Lys10 side chains are bridged by a lactam bond to form the cyclic backbone, Nle4 replaces methionine to prevent oxidative inactivation, and D-Phe7 replaces native phenylalanine to confer endopeptidase resistance and stabilise the receptor-binding pharmacophore conformation

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If you have opened an item, you can be refunded only the difference between the amount you paid and the amount you wouldve paid for a single item

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10.1016/s0021-9258(18)70608-x 51 NguyenV

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