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This new drug is a dual-agonist, which means it contains not only a GLP-1 agonist but another drug called glucose-dependent insulinotropic peptide (GIP), and the safety and benefit profile is really quite impressive. Early studies have shown it may work even better than Ozempic and Wegovy
They may have all of these things and having agents that can help both the heart and kidney to [benefit] multiple pathways is really quite exciting. The 2024 ADA Standards of Care has several recommendations for CKD prevention and treatment
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Engineering bimodal molecules that integrate GLP-1R agonism with specific pain-related mechanisms may offer innovative therapeutic options
Bioavailability is the most important factor when discussing this molecule
The final approved dosing schedule hasnt been established since the medication awaits regulatory clearance
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