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The Keytruda subcutaneous conversion is the most consequential product-hopping play in the current cycle, with potential to sustain billions in IP-protected revenue past the 2028 IV expiration
This concern arises from rodent studies indicating a link between GLP-1 and parafollicular C-cell proliferation, which could influence the risk of new-onset MTC [28]
However, no psychiatric adverse events (AES) were reported in this trial [14]
Generic semaglutide can reduce the cost barrier, but the overall treatment quality still depends on the brand, dose schedule, device type and clinical follow-up
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