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Sarris A, Cortes J, Kantarjian H, Pierce S, Smith T, Keating M, Koller C, Kornblau S, O'Brien S, Andreeff M

If I have genetic variants affecting glutathione enzymes, does that mean I need supplementation

The outcomes of the in vitro and in vivo studies indicate that several botanicals such as Gingko biloba, Centella asiatica, Ocimum sanctum, Panax ginseng, Emblica officinalis, Phyllanthus amarus, Piper longum, Tinospora cordifoila, Mentha arvensis, Mentha piperita, Syzygium cumini, Zingiber officinale, Ageratum conyzoides, Aegle marmelos and Piper betle protect against radiation-induced lethality, lipid peroxidation, and DNA damage

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32 Overall, we found significantly decreased reduced glutathione concentrations (as measured in erythrocytes) in ill dogs (n = 61) compared to healthy dogs (n = 37), with significantly greater glutathione deficiency with increased severity of disease

Cancer Res (2003) 63(3):6216