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Additionally, the medications' effects on nausea and the gastrointestinal system may create aversions to certain foods or alter the subjective experience of eating

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However, the review noted that more recent studies showed smaller treatment effects than earlier ones, and longer studies showed smaller effects than shorter ones

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Study Highlights Improvements and Differences The study analyzed the effects of semaglutide 2.4 mg administered to participants once weekly vs placebo on the STEP-HFpEF programs dual primary and confirmatory secondary, and exploratory outcomes by sex