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Although current evidence supports broad applicability across BMI, diabetes status, and fibrosis stages F2-F3, subgroup analyses suggest attenuated responses in non-obese patients and in certain ethnic groups (Hispanic patients in ESSENCE), emphasizing the need for precision medicine approaches incorporating anthropometric, genetic (e.g., PNPLA3, HSD17B13), and metabolic profiling

But until human studies are done, it remains on the frontier of regenerative medicine

Alorfi NM, Algarni AS

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If thats the case is it pregnancy safe now