| 2014 | Clinical Nutrition 6Vitamin D: A Micronutrient Regulating Genes Carsten Carlberg | 2019 | Current Pharmaceutical Design 7Comparison of menaquinone-4 and menaquinone-7 bioavailability in healthy women Sato et al
Cardiovasc Diabetol 16:48 Tanaka A, Shimabukuro M, Machii N, Teragawa H, Okada Y, Shima KR, Takamura T, Taguchi I, Hisauchi I, Toyoda S, Matsuzawa Y, Tomiyama H, Yamaoka-Tojo M, Ueda S, Higashi Y, Node K (2020) Secondary analyses to assess the profound effects of empagliflozin on endothelial function in patients with type 2 diabetes and established cardiovascular diseases: The placebo-controlled double-blind randomized effect of empagliflozin on endothelial function in cardiovascular high risk diabetes mellitus: Multi-center placebo-controlled double-blind randomized trial
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Both are FDA-approved, supported by large-scale clinical trials, and have demonstrated superior results compared to older weight management medications
JAMA Network
The side-effects are generally not very serious but can be sufficiently troublesome to require phasing in the doses during the early stages of treatment