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The International Council for Harmonisation (ICH) has developed guidelines applicable to peptide therapeutics, reducing duplicative requirements across regulatory jurisdictions
No probiotic has been conclusively shown to produce meaningful or sustained weight loss on its own
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However, long-term studies specifically tracking extended use are lacking
All statistical analyses, except for the calculation of the integrated OR for the primary outcome, were performed using the IBM SPSS Statistics software (version 28.0
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