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At therapeutic doses, GLP-1 drugs cross the blood-brain barrier and dampen dopamine signaling in the brains core reward center, making addictive substances less rewarding

Several population-based studies have evaluated thousands of patients treated with GLP-1 receptor agonists across multiple countries

To date, 22 participants have been treated in the REVEAL-1 Cohort and are included in safety and efficacy analyses

Pregnancy stop the medication and contact your physician immediately

An electronic decision support tool was shown to improve adherence to guidelines during simulation of management of LAST and may be of benefit during actual cases

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