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Apart from lipid biosynthesis, another critical pro-inflammatory process that NADPH supports in myeloid cells is the production of cytotoxic, diffusive reactive radicals, such as reactive oxygen species (ROS) via NADPH oxidases (NOXes), as well as nitric oxide ( NO) via nitric oxide synthases (NOSes)
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The sections that follow explain each row in beginner-friendly terms, starting with what each peptide actually is
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Lancet 2021;398:1811-1824
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