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Tosti, A., Iorizzo, M., Botta, G

Application Areas Studies of antioxidant mechanisms and intracellular glutathione metabolism

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However, in Vitis flexuosa different GTSs may play diverse roles in pathogen defense, since only one out of five characterized GST genes was induced, while expression of the other GSTs was down-regulated following infection by the necrotrophic fungi B

A phase I trial of PX-12, a small-molecule inhibitor of thioredoxin-1, administered as a 72-hour infusion every 21 days in patients with advanced cancers refractory to standard therapy

But it is worth being precise: these are proposed and studied mechanisms, not settled clinical facts