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These are animal doses by body weight and do not convert into a safe human dose
All animal experiments were approved by the Laboratory Animal Management and Ethics Committee of Fujian Medical University with approved number IACUC FJMU 2023-Y-0719 and were performed in accordance with the China Guide for the Protection and Use of Laboratory Animals
Each one has a different underlying mechanism, a different timeline, and a different optimal treatment
Hohenfellner K, Niessl C, Haffner D, Oh J, Okorn C, Palm K, Schlingmann KP, Wygoda S, Gahl WA (2022) Beneficial effects of starting oral cysteamine treatment in the first 2 months of life on glomerular and tubular kidney function in infantile nephropathic cystinosis
Over the last decades, significant technological progress in 3D conformal radiation treatments, such as stereotactic (body) radiotherapy (SBRT), intensity-modulated radiation therapy (IMRT), and image-guided radiation therapy (IGRT), has enabled the exact release of matching radiation doses to the accurate places of the tumor while minimizing radiation exposure of surrounding normal tissue [30, 31]
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