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Description

Prior to its release from hepatocytes, a portion of the ANGPTL3 proprotein is cleaved into N-terminal and C-terminal fragments via the action of the proprotein convertase subtilisin/kexin type (PCSK) family member enzyme, furin (encoded by the FURIN gene)

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This dual approach would foster a more robust and durable AIM needed for long-term disease control

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The organic phase (bottom layer) was transferred into a new tube and evaporated with nitrogen gas

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The risk is suboptimal weight loss progress, not toxicity

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