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Because the vast array of molecular and cellular mechanisms modulated by these two new drug classes often intercept in pathophysiological background of chronic cardiovascular and neurodegenerative diseases, it is possible that any future new anti-diabetic drug may be also relevant for cardiometabolic and cognitive decline, independently from the anti-diabetic action

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In addition to signaling in the gut, activation of SCFAs-binding receptors might be important also in the adipose tissue

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