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Then, in 2015, Lee and colleagues identified a previously overlooked open reading frame within the 12S ribosomal RNA gene of mtDNA and found that it encodes a functional peptide, MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) [1]

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Eating more oily fish with a plant-based diet low in saturated fats may benefit patients who have CKD or those at risk of developing it (Huang, Lindholm 2013)

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