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B., Lathigara, D

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Next-generation compounds are also entering clinical trials

Abbreviations API: Active pharmaceutical ingredient BSA: Bovine serum albumin C8: Caprylic acid Caco-2: Human colon adenocarcinoma cell line CO: Castor oil COL: Colistin DLS: Dynamic light scattering DOC: Docusate EE: Encapsulation efficiency ELA: Ethyl lauroyl arginate FaSSGF: Fasted-state simulated gastric fluid FCS: Fetal calve serum FTIR: Fourier-transformed infrared spectroscopy GLP-1: Glucagon like peptide-1 GMCC: Glycerol monocaprylocaprate GML: Glycerol monolinoleate HBS: HEPES buffered saline HEPES: 4-(2-Hydroxyethyl)-1-piperazineethanesulfonic acid HIP: Hydrophobic ion pair(s) HPLC: High pressure liquid chromatography LR: Lumogen Red LY: Lumogen Yellow LYS: Lysozyme NC: Nanocarrier P app : Apparent permeability coefficient PBS: Phosphate buffered saline PDI: Polydispersity index PE: Precipitation efficiency PEG: Polyethylene glycol RCF: Relative centrifugal force rCMC: Reverse critical micelle concentration Red MEM: Red minimum essential medium RM: Reverse micelles RSD: Relative standard deviation RT: Room temperature SEDDS: Self-emulsifying drug delivery systems TCNQ: 7:7:8:8-tetracyanodimethane TEER: Transepithelial electronic resistance UV: Ultraviolet References Haddadzadegan S, Dorkoosh F, Bernkop-Schnrch A

Special Situations That Need More Testing Sometimes you need blood tests more often than normal

Recovery and downtime are significantly less as well