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In a statement, the Danish drugmaker said that the process of closing down FLOW is already underway, coming after its independent data safety monitoring committee concluded that the results met certain pre-specified criteria for stopping the trial early for efficacy. The large-scale trial started in 2019 and has enrolled 3,534 subjects at hundreds of sites across 28 countries, aiming to show that a once-weekly subcutaneous dose of Ozempic can reduce a compositive primary endpoint covering a battery of kidney outcomes
However, it is extremely expensive ($23,000 for 30 mg according to Epocrates
Ozempic is normally recommended as a second-line treatment
Semaglutide mimics a natural hormone (GLP-1) that targets the brain's appetite regulation centers
Recommended daily dosage: 600 to 2,500 mg
Of course, lifestyle will always be foundational to everything that we do in cardiovascular disease prevention, including the management of obesity, said Martha Gulati, MD, Vice Chair of the scientific statement and director of prevention at Cedars-Sinai in Los Angeles, California
