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Importantly, localized increases in GLP-1, such as that occur in the gut and portal vein, often have a more profound effect than systemic elevations, emphasizing the therapeutic potential of targeting regional activity rather than relying solely on systemic concentrations
Participants were further divided based on their baseline use of SGLT2i (SGLT2i users n=2596 and SGLT2i non-users n=7054)
The concern is that the word can make an imprecise strategy sound advanced
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