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The lethal dose threshold (LD1) was never achieved in animal safety studies meaning researchers could not identify a dose lethal to 1% of test subjects
meaning that animal studies have shown some adverse effect or there are no well-controlled studies in humans, but potential benefits may warrant use despite potential risks
Adverse reactions following intramuscular (IM) injection have included anxiety, mild transient diarrhea, ataxia, nervousness, pruritus, transitory exanthema, and a feeling of swelling of the entire body
It also acts as an anti-inflammatory in some of the animals on which it has been tested
15 The authors of the study propose OTA may contribute to the neurodegenerative diseases Azheimers dementia and Parkinsons disease
