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Clinicians might consider preferring GLP-1 receptor agonists over other diabetes treatments, such as insulin, for patients at high risk of obesity-associated cancers. Wang and colleagues conducted a retrospective cohort study of deidentified electronic health records on the TriNetX platform

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15 GSSG is unable to perform antioxidant functions but can be converted back to rGSH by glutathione reductase (GSR), 15,17,18 which requires the oxidation of NADPH to NADP+

30 In the sirtuin family of proteins, NAD mediates deacetylation, demalonylation/desuccinylation, and ADP-ribosylation of target proteins

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