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Granata et al
46 High intratumoral expression of CYP3A4 can accelerate the metabolic inactivation of chemotherapeutic agents such as paclitaxel and docetaxel, thereby reducing local drug bioavailability, diminishing therapeutic efficacy, and ultimately contributing to drug resistance
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The plates were designed such that there was no sex bias, and samples from selected sex- and age-matched UFMs were prepared simultaneously to those from ND individuals, in a blinded fashion, and randomised for the order of analysis
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