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The TRIUMPH-4 data reveal that nearly 1 in 4 patients on the highest dose lost 35% of body weight, not just the average ~28.7%

[6] Patients should acknowledge that any chronic illness, including type 2 diabetes, carries an increased risk of depression and anxiety

Safety is always our priority, especially for young patients

TRIUMPH-4 (28.7% weight loss, knee OA population, December 2025), TRIUMPH-1 (28.3%, general obesity, May 2026), TRANSCEND-T2D-1 (-2.0% HbA1c, 16.8% weight loss, June 2026), TRIUMPH-2 (20.8% weight loss, obesity + diabetes, July 23, 2026), and TRIUMPH-3 (22.6% weight loss, obesity + cardiovascular disease, July 23, 2026) have all reported positive results

PMID: 39852403

The association between impulsivity and violent behavior was about 62% weaker among current users compared with former users