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For example, in chronic granulomatous disease with fungal infections, the Dectin-1 C-type lectin receptor, which recognizes -glucans, and TLRs mediate cytokine responses in wild-type murine neutrophils through the activation of tyrosine phosphatase PTPN11-SYK and downstream caspase recruitment domain family member 9 (CARD9)-dependent NF-B as well as CARD9-independent JNK-c-Jun pathways
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Song N, Wang J, Jiang H, Xie J
Granulocytic leukemiahepatic parenchyma infiltrated and replaced by a monomorphic population of neutrophils or neutrophil precursors
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