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Several simple strategies exist to create meaningful improvements in vitamin B12 absorption

You use the entire vial, nothing wasted, and then reconstitute a fresh vial for the next dose level

Adjustment should be systematic rather than reactive

If the diagnosis does not justify the injection, the claim is denied regardless of procedural accuracy

High-dose oral supplements (often 10002000 micrograms daily) or intramuscular injections (typically 1mg hydroxocobalamin) used to treat pernicious anaemia or deficiency states can temporarily elevate serum levels

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