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Inhibition of Lipogenesis (The Pull): It inhibits Lipoprotein Lipase (LPL) and Acetyl-CoA Carboxylase (ACC), preventing the uptake of dietary fat and the synthesis of new triglycerides

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The metabolic benefits extend to cellular energy regulation, where NNMT inhibition increases intracellular NAD+ levels by 1.2-1.6 fold

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