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Doses above ~500 mcg/day are not generally linked to added benefit in the reference literature, and none of this reflects proven human efficacy
Pernicious anaemia, atrophic gastritis, proton pump inhibitors, metformin, and gastrointestinal surgery significantly impair B12 absorption
Its important to consult with a healthcare professional before considering vitamin B12 injections, as they can help determine the appropriate dosage and administration method based on individual needs and medical history
Rarely reported symptoms may include mild skin reactions, gastrointestinal disturbance, or headache, typically following high-dose intramuscular injections
Anti-ARA 290 titers at baseline and after 28 d were negative
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