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Interestingly, GLP-1RA drugs act on receptors that are expressed in brain areas involved in impulse control, reward and addiction potentially explaining their effectiveness in curbing appetite and addiction disorders, said Al-Aly, the director of the Clinical Epidemiology Center at the VA St
The glucagon receptor, in particular, has effects on heart rate that have drawn regulatory scrutiny and contributed to the extended timeline for FDA review
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Microbiol 55 , 165199 (2001)