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Glutathione deficiency correlates with chronic disease and can be replenished from exogenous sources, such as natural glutathione in food and glutathione supplements

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The current hypothesis is that because adequate concentrations of GSH are required for proper lymphocyte function, a deficiency in GSH may contribute to the immunodeficiency seen in the later stages of HIV infection

doi:10.7326/0003-4819-152-2-201001190-00008

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