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Muscle aches and weakness often trace back to magnesium or vitamin D insufficiency
The adult onset form is associated with progressive neurodegeneration characterized by ataxia, spasticity, and sometimes dementia
Opposite to what was found in male SE offspring, the apoptotic marker caspase-3 level was not changed in females brain suggesting better persevered cell integrity (Chandler et al., There is a significant gender difference in response to maternal SE as shown by us previously (Chan et al., 2000)
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This is because females inherit two X chromosomes, so the effects of a defective gene on one X chromosome can be overridden by a healthy gene on the other
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